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TribioScience | SKU: TBI2935-5MG

YM-58483, CRAC channel blocker (TBI2935)

Name: YM-58483, CRAC channel blocker (TBI2935)
Brand: TribioScience
SKU: TBI2935-5MG
Price: 144.0 USD
Availability: InStock

$144.00

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Product Description

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TribioScience

YM-58483, CRAC channel blocker (TBI2935)

From $144.00

Description

Product Details

Formal Name: N-[4-[3,5-Bis(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-4-methyl-1,2,3-thiadiazole-5-carboxamide

Alternate Names: BTP2

Molecular Formula: C₁₅H₉F₆N₅OS

Formula Weight: 421.30

CAS Number: 223499-30-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 40 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

CRAC channel blocker

Functions

YM-58483 is a CRAC (calcium release-activated calcium) channel blocker, a prototypic store-operated calcium channel. Inhibits antigen-induced histamine release via modulation of mast cell responses. Displays potent analgesic actions in various pain models in mice and is orally active. Inhibits T cell-mediated immune responses in vivo.