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TribioScience  |  SKU: TBI5112-10MG

Xanomeline tartrate, Selective M1 Muscarinic agonist (TBI5112)

$126.00
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TribioScience

Xanomeline tartrate, Selective M1 Muscarinic agonist (TBI5112)

From $126.00

Description

Product Details

Formal Name: 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine, tartrate

Alternate Names: LY246708 tartrate

Molecular Formula: C14H23N3OS

Formula Weight: 431.50

CAS Number: 152854-19-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (45 mg/ml); or Water (70 mg/ml)

Storage: -20°C

Stability: ≥ 2 years.

Applications

Selective M1 Muscarinic agonist

Functions

A functionally-selective M1 muscarinic receptor agonist, EC50=0.3, 92.5, 5, 52 and 42 nM for M1, M2, M3, M4 and M5 respectively. Displays positive cognitive and behavioral effects in schizophrenia and Alzheimer’s disease. Suppresses proinflammatory cytokine responses and improves survival in sepsis. Displays potent analgesic activity in rodent models of chronic inflammatory and neuropathic pain.

Application Procedures

First dissolved in DMSO (45 mg/ml); or Water (70 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or water may be stored at -20°C for up to 2 months.

Option

  • 10 MG
  • 50 MG
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