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TribioScience  |  SKU: TBI4472-10MG

Umifenovir, Antiviral agent (TBI4472)

$90.00
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TribioScience

Umifenovir, Antiviral agent (TBI4472)

From $90.00

Description

Product Details

Formal Name: 6-bromo-4-[(dimethylamino)methyl]-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic acid, ethyl ester, monohydrochloride

Alternate Names: Arbidol

Molecular Formula: C22H25BrN2O3S • HCl

Formula Weight: 513.90

CAS Number: 131707-23-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to at least 15 mg/ml) or in Ethanol (up to at least 10 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Antiviral agent

Functions

Umifenovir (131707-23-8) is a broad-spectrum antiviral medication. It has shown activity against influenza A,B,and C, respiratory syncytial, SARS-CoV, adeno, parainfluenza type 5, polio, rhino, coxsackie, hanta, chikungungya, hepatitis B and C viruses. It blocks hemagglutinin-mediated membrane fusion of influenza virus particles. Umifenovir has recently been shown to inhibit SARS-CoV2 infection by blocking virus entry as well as release from endolysosomes during intracellular trafficking. It has been suggested that Umifenovir may block trimerization of the spike glycoprotein, a key step in host cell adhesion.

Application Procedures

First dissolved in DMSO (up to at least 15 mg/ml) or in Ethanol (up to at least 10 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Option

  • 10 MG
  • 50 MG
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