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TribioScience  |  SKU: TBI2179-5MG

U0126, MEK1 and MEK2 inhibitor (TBI2179)

$162.00
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TribioScience

U0126, MEK1 and MEK2 inhibitor (TBI2179)

From $162.00

Description

Product Details

Formal Name: 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene

Molecular Formula: C18H16N6S2

Formula Weight: 380.49

CAS Number: 109511-58-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 200 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

MEK1 and MEK2 inhibitor

Functions

Highly selective inhibitor of MEK1 and MEK2 in vitro and in vivo. Unlike PD98059, which only inhibits the activation of MEK1 and MEK2, U0126 inhibits both the active and inactive forms of the MEK enzymes. Inhibition of MEK1 and MEK2 has been demonstrated to enhance the self renewal of stem cells.

Application Procedures

First dissolved in DMSO (up to 200 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.

Option

  • 5 MG
  • 25 MG
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