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TribioScience  |  SKU: TBI1115-100MG

Thalidomide, E3 Ubiquitin ligase inhibitor (TBI1115)

$90.00
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Product Description


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TribioScience

Thalidomide, E3 Ubiquitin ligase inhibitor (TBI1115)

From $90.00

Description

Product Details

Formal Name: N-(2,6-Dioxo-3-piperidinyl)phthalimide, racemic

Molecular Formula: C13H10N2O4

Formula Weight: 326.82

CAS Number: 50-35-1

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 5 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

E3 Ubiquitin ligase inhibitor

Functions

Binds to the E3 ubiquitin ligase complex formed between CRBN, DDB1 and Cul4A, and inhibits the ligase activity. Inhibits TNF synthesis and FGF-induced angiogenesis. Cell permeable. Handle with caution, compound is teratogenic.

Application Procedures

First dissolved in DMSO (up to 5 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.

Option

  • 100 MG
  • 500 MG
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