Welcome to Astor Scientific

New collections added! Learn more

TribioScience  |  SKU: TBI3909-5MG

TH301, CRY2 stabilizer (selective) (TBI3909)

$144.00
Shipping calculated at checkout.


Care information

Display general product information or specific product information using metafields.

Delivery and Shipping

Add some general information about your delivery and shipping policies.

Payment & Security

Payment methods

  • American Express
  • Apple Pay
  • Diners Club
  • Discover
  • Google Pay
  • Mastercard
  • PayPal
  • Shop Pay
  • Venmo
  • Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.


Product Description


Product Reviews

Customer Reviews

Be the first to write a review
0%
(0)
0%
(0)
0%
(0)
0%
(0)
0%
(0)
TribioScience

TH301, CRY2 stabilizer (selective) (TBI3909)

From $144.00

Description

Product Details

Formal Name: 1-(4-Chlorophenyl)-N-[2,6-dihydro-2-(4-methoxyphenyl)-5,5-dioxido-4H-thieno[3,4-c]pyrazol-3-yl]cyclopentanecarboxamide

Molecular Formula: C24H24ClN3O4S

Formula Weight: 486.00

CAS Number: 450338-32-6

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

CRY2 stabilizer (selective)

Functions

An isoform-selective stabilizer of the circadian clock protein CRY2. Dose-dependently lengthened the circadian period in Bmal1-dLuc and Per2-dLuc reporter cells. Has been used in combination with CRY1 stabilizer KL101 to demonstrate the differential gatekeeper conformations of the two proteins. TH301 strongly enhanced rosiglitazone-dependent brown adipocyte differentiation revealing the importance of CRY-dependent regulation of energy metabolism and a possible new lead for anti-obesity therapeutics.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Option

  • 5 MG
  • 25 MG
View product
close
close
I have a question
sparkles
close
product
Hello! I am very interested in this product.
gift
Special Deal!
sparkles