Temsirolimus, mTOR inhibitor (TBI3261)

Description

Product Details

Formal Name: 42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate] rapamycin

Molecular Formula: C₅₆H₈₇NO₁₆

Formula Weight: 1030.3

CAS Number: 162635-04-3

Purity: >95%

Formulation: powder

Solubility: Soluble in DMSO (up to 12.5 mg/ml), ethanol (up to 10 mg/ml), and DMF (up to 20 mg/ml)

Storage: -20°C

Stability: ≥ 4 years.

Applications

mTOR(mammalian target of rapamycin) inhibitor

Functions

Temsirolimus specifically inhibits mTOR signaling and inhibits the growth and proliferation of various breast cancer cell lines.

Procedures

First dissolved in DMSO (up to 12.5 mg/ml), ethanol (up to 10 mg/ml), and DMF (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 day.