Taxol, Microtubule stabilizing agent (TBI2095)

Description

Product Details

Alternate Names: Paclitaxel

Molecular Formula: C₄₇H₅₁NO₁₄

Formula Weight: 853.91

CAS Number: 33069-62-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 50 mg/ml).

Storage: -20°C

Stability: ≥ 1 year.

Applications

Microtubule stabilizing agent

Functions

Taxol is a clinically useful cancer chemotherapeutic agent for the treatment of breast, non-small cell lung and ovarian cancer. It acts as a promoter of tubulin polymerization and stabilizes microtubules in vitro and in vivo resulting in arrest of cells in the G2 and M phase of the cell cycle.

Application Procedures

First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20° for up to 3 months.