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TribioScience | SKU: TBI1122-5MG

Sulindac sulfone, Modulates beta-catenin-mediated effects (TBI1122)

Name: Sulindac sulfone, Modulates beta-catenin-mediated effects (TBI1122)
Brand: TribioScience
SKU: TBI1122-5MG
Price: 90.0 USD
Availability: InStock

$90.00

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TribioScience

Sulindac sulfone, Modulates beta-catenin-mediated effects (TBI1122)

From $90.00

Description

Product Details

Formal Name: (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfonyl)benzylidene]indene-3-acetic acid

Molecular Formula: C₂₀H₁₇FO₄S

Formula Weight: 372.41

CAS Number: 59864-04-9

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Modulates beta-catenin-mediated effects

Functions

Metabolite of the cyclooxygenase inhibitor sulindac that induces apoptosis via inhibition of type 5 phosphodiesterases. Sulindac sulfone does not inhibit cyclooxygenase at physiological concentrations but does inhibit K-ras-dependent cyclooxygenase-2 expression in colon cancer cells.