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TribioScience | SKU: TBI4050-100MG

SKF-525A HCl, Cytochrome P450 inhibitor (TBI4050)

Name: SKF-525A HCl, Cytochrome P450 inhibitor (TBI4050)
Brand: TribioScience
SKU: TBI4050-100MG
Price: 90.0 USD
Availability: InStock

$90.00

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TribioScience

SKF-525A HCl, Cytochrome P450 inhibitor (TBI4050)

From $90.00

Description

Product Details

Formal Name: N,N-Diethylaminoethyl-2,2-diphenylvalerate hydrochloride

Alternate Names: Proadifen

Molecular Formula: C₂₃H₃₁NO₂ ∙ HCl

Formula Weight: 390.00

CAS Number: 62-68-0

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Cytochrome P450 inhibitor

Functions

Broad-spectrum cytochrome P450 monoxygenase inhibitor that also blocks the acetylcholine receptor (IC50 = 19 µM). Inhibits nitric oxide synthase (NOS). Also inhibits glibenclamide-sensitive K+ channels (IC50 = 9.8 µM) in Xenopus oocytes. Increases inflammatory cytokine expression in Müller glial cells and inhibits the excitability of rat 5-HT neurons.