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TribioScience  |  SKU: ASTBI5483-10MG

SKA-31, Potassium channel activator (TBI5483)

$108.00
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Product Description


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TribioScience

SKA-31, Potassium channel activator (TBI5483)

From $108.00

Description

Product Details

Formal Name: Naphtho[1,2-d]thiazol-2-ylamine

Alternate Names: 2-Aminonapthiazole

Molecular Formula: C11H8N2S

Formula Weight: 200.10

CAS Number: 40172-65-4

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (40 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

Potassium channel activator

Functions

KCa3.1 and KCa2 potassium channel activator (EC50 =260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively). Enhances acetylcholine-induced EDHF dilator response in mouse carotid arteries and lowers blood pressure in mouse models at 30 mg/Kg. Evokes robust vasodilation in rat mesenteric arteries.

Application Procedures

First dissolved in DMSO (40 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 2 months.

Option

  • 10 MG
  • 50 MG
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