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TribioScience  |  SKU: TBI1054-10MG

SC-514, IKK-2 inhibitor (TBI1054)

$117.00
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TribioScience

SC-514, IKK-2 inhibitor (TBI1054)

From $117.00

Description

Product Details

Formal Name: 5-(Thien-3-yl)-3-aminothiophene-2-carboxamide

Molecular Formula: C9H8N2OS2

Formula Weight: 224.30

CAS Number: 354812-17-2

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml)

Storage: RT

Stability: ≥ 1 year.

Applications

IKK-2 inhibitor

Functions

Reversible, competitive inhibitor of IKK2 (IC50 = 11.2 µM). Has not been demonstrated to inhibit other IKK isoforms, or other kinases. Displays dose-dependent inhibition of the transcription of NK-κB dependent genes in cell culture.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.

Option

  • 10 MG
  • 50 MG
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