Saxagliptin HCl, DPP-IV inhibitor (TBI4076)

Description

Product Details

Formal Name: (1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile, hydrochloride

Alternate Names: BMS-477118

Molecular Formula: C₁₈H₂₅N₃O₂·HCl

Formula Weight: 416.40

CAS Number: 709031-78-7

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 20 mg/ml)

Storage: -20°C

Stability: ≥ 1 year.

Applications

DPP-IV inhibitor

Functions

Saxagliptin is a clinically useful DPPIV inhibitor for the treatment of diabetes. Human DPP-IV Ki = 0.6 nM.

Application Procedures

First dissolved in DMSO (up to 20 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.