Rottlerin, Autophagy inducer (TBI1341)

Description

Product Details

Formal Name: 3′-[(8-Cinnamoyl-5,7-dihydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-2′,4′,6′-trihydroxy-5′-methylacetophenone

Molecular Formula: C₃₀H₂₈O₈

Formula Weight: 516.65

CAS Number: 82-08-6

Purity: >98%

Formulation: Powder

Solubility: Soluble in DMSO (up to 50 mg/ml).

Storage: Room temperature

Stability: ≥ 2 years.

Applications

Autophagy inducer

Functions

Reported to inhibit PKCδ selectively however this result has been called into question. Displays neuroprotective effects. Induces autophagy. Cell permeable.

Application Procedures

First dissolved in DMSO (up to 50 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.