Regorafenib, Multi-kinase inhibitor (TBI3224)

Description

Product Details

Formal Name: 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide

Molecular Formula: C₂₁H₁₅ClF₄N₄O₃

Formula Weight: 482.8

CAS Number: 755037-03-7

Purity: ≥98%

Formulation: powder

Solubility: Soluble in DMSO (up to 30 mg/ml), ethanol (up to 14 mg/ml), and DMF (up to 30 mg/ml)

Storage: -20°C

Stability: ≥ 4 years.

Applications

Multi-kinase inhibitor

Functions

Regorafenib is a multi-kinase inhibitor that inhibits the growth and proliferation of tumors.

Procedures

First dissolved in DMSO (up to 30 mg/ml), ethanol (up to 14 mg/ml), and DMF (up to 30 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 day.