| Product Name |
Recombinant Mouse Von Willebrand Factor (vWF) Protein |
| Product Overview |
This recombinant mouse Von Willebrand Factor (vWF) protein includes amino acids 1498-1665aa of the target gene is expressed in E.coli.The protein is supplied in liquid or lyophilized powder form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
Q8CIZ8 |
| Recommended Name |
von Willebrand factor |
| Gene Name |
Vwf |
| Synonyms |
F8VWF; VWD; von Willebrand antigen 2 |
| Species |
Mouse |
| Predicted Molecular Mass |
20 kDa |
| Expression System |
E.coli |
| Expression Range |
1498-1665aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Liquid or Lyophilized powder |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular, Cancer |
| Target Function |
Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma. |
| Subcellular Location |
Secreted. Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity |
Plasma. Expressed in liver. |
