| Description |
Recombinant Mouse TRAIL/TNFRSF10 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Pro118-Asn291. |
| Purity |
> 95% as determined by Tris-Bis PAGE |
| Accession |
P50592 |
| Target Symbol |
TRAIL/TNFRSF10 |
| Synonyms |
Apo-2L; TRAIL; CD253; TNFSF10; Apo-2 ligand; APO2L; TL2 |
| Species |
Mouse |
| Expression System |
E. coli |
| Tag |
N-His |
| Expression Range |
Pro118-Asn291 |
| Mol. Weight |
The protein has a predicted MW of 30.6 kDa same as Tris-Bis PAGE result. |
| Form |
Liquid |
| Formulation |
Supplied as 0.22um filtered solution in 0.1M Glycine, 150mM NaCl, 10% Glycerol (pH 3.0). |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Activity |
The affinity constant of 0.62 uM as determined in SPR assay (Biacore T200). Contact us for detailed testing images. |
| Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping |
Shipped with dry ice. |
| Gene Background |
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based cancer therapies, which include recombinant forms of TRAIL, TRAIL receptor agonists, and other therapeutic agents. |
