| Product Name |
Recombinant Mouse Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) Protein |
| Product Overview |
This recombinant mouse Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) protein includes amino acids 20-211aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P39876 |
| Recommended Name |
Metalloproteinase inhibitor 3 |
| Gene Name |
Timp3 |
| Synonyms |
Sun, Timp-3，SFD |
| Species |
Mouse |
| Predicted Molecular Mass |
22 kDa |
| Expression System |
E.coli |
| Expression Range |
20-211aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. |
| Subcellular Location |
Secreted, extracellular space, extracellular matrix. |
| Protein Family |
Protease inhibitor I35 (TIMP) family |
| Tissue Specificity |
Highest levels are found in kidney, lung and brain followed by ovary and uterus. Low levels are found in bone. |
