Description |
Recombinant Mouse Nectin-4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly31-Ser347. |
Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Accession |
Q8R007 |
Target Symbol |
Nectin-4 |
Synonyms |
EDSS1; LNIR; Nectin4; PRR4; NECTIN4; PVRL4 |
Species |
Mouse |
Expression System |
HEK293 |
Tag |
C-His |
Expression Range |
Gly31-Ser347 |
Mol. Weight |
The protein has a predicted MW of 35.4 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result. |
Form |
Lyophilized |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Activity |
Immobilized Mouse Nectin-4, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Human Nectin-1, hFc Tag with the EC50 of 0.16ug/ml determined by ELISA. Contact us for detailed testing images. |
Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Shipping |
Shipped at ambient temperature. |
Gene Background |
Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.(Microbial infection) Acts as a receptor for measles virus. |