| Description |
Recombinant Mouse Midkine Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys23-Asp140. |
| Purity |
> 95% as determined by Tris-Bis PAGE |
| Accession |
P12025 |
| Target Symbol |
Midkine |
| Synonyms |
MK; Amphiregulin-associated protein; ARAP; Midgestation and kidney protein; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; MDK; MEK; MK1; MKARAP; NEGF2 |
| Species |
Mouse |
| Expression System |
E. coli |
| Tag |
N-His |
| Expression Range |
Lys23-Asp140 |
| Mol. Weight |
The protein has a predicted MW of 14.03 kDa. The protein migrates to 17-20 kDa based on Tris-Bis PAGE result. |
| Form |
Liquid |
| Formulation |
Supplied as 0.22um filtered solution in PBS, 350mM NaCl, 200mM L-arginine (pH 7.4). |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping |
Shipped with dry ice. |
| Gene Background |
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. |
