| Description |
Recombinant Mouse MFAP4 Protein is expressed from HEK293 with His tag and Flag tag at the N-Terminus.It contains Gln23-Ala257. |
| Purity |
> 95% as determined by Tris-Bis PAGE |
| Accession |
Q9D1H9 |
| Target Symbol |
MFAP4 |
| Synonyms |
Microfibril-associated glycoprotein 4；Mfap4 |
| Species |
Mouse |
| Expression System |
HEK293 |
| Tag |
N-His-Flag |
| Expression Range |
Gln23-Ala257 |
| Mol. Weight |
The protein has a predicted MW of 28.7 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result. |
| Form |
Lyophilized |
| Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping |
Shipped at ambient temperature. |
| Gene Background |
Microfibril-associated glycoprotein 4 (MFAP4) is an extracellular matrix protein belonging to the fibrinogen-related protein superfamily. MFAP4 is produced by vascular smooth muscle cells and is highly enriched in the blood vessels of the heart and lung, where it is thought to contribute to the structure and function of elastic fibers. Genetic studies in humans have implicated MFAP4 in the pathogenesis of Smith-Magenis syndrome, in which patients present with multiple congenital abnormalities and mental retardation, as well as in the severe cardiac malformation left-sided congenital heart disease. |
