Product Name |
Recombinant Mouse Lysyl Oxidase (LOX) Protein |
Product Overview |
This recombinant mouse Lysyl Oxidase (LOX) protein includes amino acids 207-411aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
Target Uniprot Id |
P28301 |
Recommended Name |
Protein-lysine 6-oxidase |
Gene Name |
Lox |
Synonyms |
Rrg |
Species |
Mouse |
Predicted Molecular Mass |
54 kDa |
Expression System |
E.coli |
Expression Range |
207-411aa |
Tag |
N-His-GST |
Purity |
>90% |
Formulation |
Lyophilized |
Buffer |
PBS |
Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
Research Area |
Signal Transduction |
Target Function |
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. |
Subcellular Location |
Secreted. Secreted, extracellular space. |
Protein Family |
Lysyl oxidase family |
Tissue Specificity |
Expressed in aorta (at protein level). Expressed in embryonic, juvenil and adult aorta. |