| Product Name |
Recombinant Mouse Interleukin 1 Receptor Antagonist (IL1RA/Il1rn) Protein |
| Product Overview |
This recombinant mouse Interleukin 1 Receptor Antagonist (IL1RA/Il1rn) protein includes amino acids 27-178aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P25085 |
| Recommended Name |
Interleukin-1 receptor antagonist protein |
| Gene Name |
Il1rn |
| Synonyms |
Interleukin 1 receptor antagonist, F630041P17Rik, IL-1ra. |
| Species |
Mouse |
| Predicted Molecular Mass |
20.0 kDa |
| Expression System |
E.coli |
| Expression Range |
27-178aa |
| Tag |
N-6His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. |
| Subcellular Location |
[Isoform 1]: Secreted.; [Isoform 2]: Cytoplasm. |
| Protein Family |
IL-1 family |
