| Product Name |
Recombinant Mouse IL-15 Receptor Subunit α/CD215/IL-15RA (Il15ra) Protein |
| Product Overview |
This recombinant mouse IL-15 Receptor Subunit α/CD215/IL-15RA (Il15ra) protein includes amino acids 33-205aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q60819 |
| Recommended Name |
Interleukin-15 receptor subunit alpha |
| Gene Name |
Il15ra |
| Synonyms |
Interleukin-15 receptor subunit alpha;Il15ra;sIL-15 receptor subunit alpha |
| Species |
Mouse |
| Predicted Molecular Mass |
45.5 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
33-205aa |
| Tag |
C-Fc |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology |
| Target Function |
High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. In neutrophils, binds and activates kinase SYK in response to IL15 stimulation. In neutrophils, required for IL15-induced phagocytosis in a SYK-dependent manner. |
| Subcellular Location |
Membrane; Single-pass type I membrane protein. Nucleus membrane; Single-pass type I membrane protein. Cell surface.; [Soluble interleukin-15 receptor subunit alpha]: Secreted, extracellular space. |
| Tissue Specificity |
Widely expressed. |
