| Product Name |
Recombinant Mouse Heme Oxygenase 1 (HO1/Hmox1) Protein |
| Product Overview |
This recombinant mouse Heme Oxygenase 1 (HO1/Hmox1) protein includes amino acids 1-289 of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitolprior to lyophilization. |
| Target Uniprot Id |
P14901 |
| Recommended Name |
Heme oxygenase 1 |
| Gene Name |
Hmox1 |
| Synonyms |
HMOX1; Hsp32; HMOX1D |
| Species |
Mouse |
| Predicted Molecular Mass |
35kDa |
| Expression System |
E.coli |
| Expression Range |
1-289 |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS pH 7.4, 0.01% SKL, 5% Trehalose, 1% Mannitol |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cell Biology, Others |
| Target Function |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. |
| Subcellular Location |
Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. |
| Protein Family |
Heme oxygenase family |
