| Description |
Recombinant Mouse HGFA Protein (pro form) is expressed from HEK293 with His tag at the C-Terminus.It contains Gln35-Ser653. |
| Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Accession |
Q9R098 |
| Target Symbol |
HGFA |
| Synonyms |
HGF activator; HGFA; Hgfac; MGC138395; MGC138397 |
| Species |
Mouse |
| Expression System |
HEK293 |
| Tag |
C-His |
| Expression Range |
Gln35-Ser653 |
| Mol. Weight |
The protein has a predicted MW of 67.9 kDa. Due to glycosylation, the protein (pro form) migrates to 80-100 kDa based on Tris-Bis PAGE result. |
| Form |
Lyophilized |
| Formulation |
Lyophilized from 0.22um filtered solution in 20mM Tris,150mM NaCl, 2mM CaCl2 (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping |
Shipped at ambient temperature. |
| Gene Background |
Hepatocyte growth factor activator (HGFA) is a serine protease initially identified as a potent activator of hepatocyte growth factor/scatter factor. Hepatocyte growth factor/scatter factor is known to be critically involved in tissue morphogenesis, regeneration, and tumor progression, via its receptor, MET.In vivo, HGFA also activates macrophage-stimulating protein, which has roles in macrophage recruitment and inflammatory processes, cellular survival and wound healing through its receptor, RON. |
