| Description |
Recombinant Mouse GPRC5D Protein-VLP is expressed from HEK293.It contains Met1-Leu344. |
| Purity |
> 95% as determined by HPLC |
| Accession |
Q9JIL6 |
| Target Symbol |
GPRC5D VLP |
| Species |
Mouse |
| Expression System |
HEK293 |
| Expression Range |
Met1-Leu344 |
| Mol. Weight |
The target protein has a predicted MW of 39.90 kDa. |
| Form |
Liquid |
| Formulation |
Supplied as 0.22um filtered solution in PBS, 300mM L-Arginine (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
|
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Activity |
Immobilized Mouse GPRC5D VLP (100ul/well) at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.7ng/ml determined by ELISA. Contact us for detailed testing images. |
| Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping |
Shipped with dry ice. |
| Gene Background |
Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. |
