| Description |
Recombinant Mouse ECSCR Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln19-Thr130. |
| Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Accession |
Q3TZW0 |
| Target Symbol |
ECSCR |
| Synonyms |
ARIA; ECSCR; ECSM2 |
| Species |
Mouse |
| Expression System |
HEK293 |
| Tag |
C-hFc |
| Expression Range |
Gln19-Thr130 |
| Mol. Weight |
The protein has a predicted MW of 38.6 kDa. Due to glycosylation, the protein migrates to 48-68 kDa based on Tris-Bis PAGE result. |
| Form |
Lyophilized |
| Formulation |
Lyophilized from 0.22um filtered solution in 20mM Tris,150mM NaCl (pH 8.2). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping |
Shipped at ambient temperature. |
| Gene Background |
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF). |
