| Product Name |
Recombinant Mouse Chemokine C-X-C-Motif Receptor 3 (CXCR3) Protein |
| Product Overview |
This recombinant mouse Chemokine C-X-C-Motif Receptor 3 (CXCR3) protein includes amino acids 1-56+111-125+190-222+277-300aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
O88410 |
| Recommended Name |
C-X-C chemokine receptor type 3 |
| Gene Name |
Cxcr3 |
| Synonyms |
CD183; CKR-L2; CMKAR3; GPR9; IP10r; IP10-R; Mig-R; MigR; G Protein-Coupled Receptor 9; Interferon-in |
| Species |
Mouse |
| Predicted Molecular Mass |
20 kDa |
| Expression System |
E.coli |
| Expression Range |
1-56+111-125+190-222+277-300aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular |
| Target Function |
Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway. Probably promotes cell chemotaxis response. Binds to CCL21. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. |
| Protein Family |
G-protein coupled receptor 1 family |
| Tissue Specificity |
Expresses in lymphoid organs and Th1 cells. |
