| Product Name |
Recombinant Mouse Cystathionine Beta Synthase (CbS) Protein |
| Product Overview |
This recombinant mouse Cystathionine Beta Synthase (CbS) protein includes amino acids 253-547aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
Q91WT9 |
| Recommended Name |
Cystathionine beta-synthase |
| Gene Name |
Cbs |
| Synonyms |
HIP4; Beta-thionase; Serine sulfhydrase |
| Species |
Mouse |
| Predicted Molecular Mass |
37 kDa |
| Expression System |
E.coli |
| Expression Range |
253-547aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Others, Cancer |
| Target Function |
Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine. This catabolic route allows the elimination of L-methionine and the toxic metabolite L-homocysteine. Also involved in the production of hydrogen sulfide, a gasotransmitter with signaling and cytoprotective effects on neurons. |
| Subcellular Location |
Cytoplasm. Nucleus. |
| Protein Family |
Cysteine synthase/cystathionine beta-synthase family |