| Product Name |
Recombinant Human Tyrosyl tRNA Synthetase (YARS/YARS1) Protein |
| Product Overview |
This recombinant human Tyrosyl tRNA Synthetase (YARS/YARS1) protein includes amino acids 2-528aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P54577 |
| Recommended Name |
Tyrosine--tRNA ligase, cytoplasmic |
| Gene Name |
YARS1 |
| Synonyms |
CMTDIC; TYRRS; YRS; YTS; Tyrosine tRNA Ligase 1,Cytoplasmic |
| Species |
Human |
| Predicted Molecular Mass |
63 kDa |
| Expression System |
E.coli |
| Expression Range |
2-528aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Metabolism |
| Target Function |
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr). |
| Subcellular Location |
Cytoplasm. |
| Protein Family |
Class-I aminoacyl-tRNA synthetase family |
| Associated Diseases |
Charcot-Marie-Tooth disease, dominant, intermediate type, C (CMTDIC) |
