| Product Name |
Recombinant Human Eukaryotic Vascular Endothelial Growth Factor C (VEGFC) Protein |
| Product Overview |
This recombinant human Eukaryotic Vascular Endothelial Growth Factor C (VEGFC) protein includes amino acids 103-227aa of the target gene is expressed in 293F cell.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P49767 |
| Recommended Name |
Vascular endothelial growth factor C |
| Gene Name |
VEGFC |
| Synonyms |
Vascular endothelial growth factor C, Flt4-L, LMPH1D, VRP |
| Species |
Human |
| Predicted Molecular Mass |
20 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
103-227aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates KDR/VEGFR2 and FLT4/VEGFR3 receptors. |
| Subcellular Location |
Secreted. |
| Protein Family |
PDGF/VEGF growth factor family |
| Associated Diseases |
Lymphedema, hereditary, 1D (LMPH1D) |
| Tissue Specificity |
Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. |
