| Product Name |
Recombinant Human uPAR / CD87 (PLAUR) Protein |
| Product Overview |
This recombinant human uPAR / CD87 (PLAUR) protein includes amino acids 23-303aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q03405 |
| Recommended Name |
Urokinase plasminogen activator surface receptor |
| Gene Name |
PLAUR |
| Synonyms |
Urokinase Plasminogen Activator Surface Receptor; U-PAR; uPAR; Monocyte activation antigenMo3; CD87 |
| Species |
Human |
| Predicted Molecular Mass |
32.6 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
23-303aa |
| Tag |
C-6His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Acts as a receptor for urokinase plasminogen activator. Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form. |
| Subcellular Location |
Cell membrane. Cell projection, invadopodium membrane.; [Isoform 1]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 2]: Secreted. |
| Tissue Specificity |
Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain. |
