| Product Name |
Recombinant Human NKG2D Ligand 1/NKG2DL/ULBP1 Protein |
| Product Overview |
This recombinant human NKG2D Ligand 1/NKG2DL/ULBP1 protein includes amino acids 26-215aa of the target gene is expressed in HEK293 Cells.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q9BZM6 |
| Recommended Name |
UL16-binding protein 1 |
| Gene Name |
ULBP1 |
| Synonyms |
NKG2D ligand 1;NKG2DL1;ALCAN-beta;Retinoic acid early transcript 1I;UL16-binding protein 1;ULBP1 |
| Species |
Human |
| Predicted Molecular Mass |
49.4 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
26-215aa |
| Tag |
C-Fc |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cancer |
| Target Function |
Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity. |
| Subcellular Location |
Cell membrane; Lipid-anchor, GPI-anchor. Endoplasmic reticulum. |
| Protein Family |
MHC class I family |
| Tissue Specificity |
Expressed in T-cells, B-cells, erythroleukemia cell lines and in a wide range of tissues including heart, brain, lung, liver, testis, lymph node, thymus, tonsil and bone marrow. Also found in fetal heart, brain, lung and liver. |
