| Product Name |
Recombinant Human Ubiquitin Carboxyl Terminal Hydrolase L5 (UCHL5) Protein |
| Product Overview |
This recombinant human Ubiquitin Carboxyl Terminal Hydrolase L5 (UCHL5) protein includes amino acids 2-316aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q9Y5K5 |
| Recommended Name |
Ubiquitin carboxyl-terminal hydrolase isozyme L5 |
| Gene Name |
UCHL5 |
| Synonyms |
Ubiquitin carboxyl-terminal hydrolase isozyme L5, Ubiquitin carboxyl-terminal hydrolase isozyme L5, |
| Species |
Human |
| Predicted Molecular Mass |
38 kDa |
| Expression System |
E.coli |
| Expression Range |
2-316aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Epigenetics And Nuclear Signaling |
| Target Function |
Protease that specifically cleaves 'Lys-48'-linked polyubiquitin chains. Deubiquitinating enzyme associated with the 19S regulatory subunit of the 26S proteasome. Putative regulatory component of the INO80 complex; however is inactive in the INO80 complex and is activated by a transient interaction of the INO80 complex with the proteasome via ADRM1. |
| Subcellular Location |
Cytoplasm. Nucleus. Note=Associates with the proteasome 19S subunit in the cytoplasm. Associates with the INO80 complex in the nucleus. |
| Protein Family |
Peptidase C12 family |
