| Product Name |
Recombinant Human Tomoregulin 1 (TR1/TMEFF1) Protein |
| Product Overview |
This recombinant human Tomoregulin 1 (TR1/TMEFF1) protein includes amino acids 79-333aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q8IYR6 |
| Recommended Name |
Tomoregulin-1 |
| Gene Name |
TMEFF1 |
| Synonyms |
Tomoregulin-1, C9orf2, CT120.1, H7365, TR-1 |
| Species |
Human |
| Predicted Molecular Mass |
33 kDa |
| Expression System |
E.coli |
| Expression Range |
79-333aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Others |
| Target Function |
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers. |
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. |
| Protein Family |
Tomoregulin family |
| Tissue Specificity |
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. |
