| Product Name |
Recombinant Human Thioredoxin2 (TXN2) Protein |
| Product Overview |
This recombinant human Thioredoxin2 (TXN2) protein includes amino acids 60-166aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q99757 |
| Recommended Name |
Thioredoxin, mitochondrial |
| Gene Name |
TXN2 |
| Synonyms |
MTRX, TRX2, MT-TRX, Thioredoxin2 , mitochondrial thioredoxin, thioredoxin 2 precursor, Thioredoxin m |
| Species |
Human |
| Predicted Molecular Mass |
11 kDa |
| Expression System |
E.coli |
| Expression Range |
60-166aa |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Important for the control of mitochondrial reactive oxygen species homeostasis, apoptosis regulation and cell viability. Possesses a dithiol-reducing activity. |
| Subcellular Location |
Mitochondrion. |
| Protein Family |
Thioredoxin family |
| Associated Diseases |
Combined oxidative phosphorylation deficiency 29 (COXPD29) |
| Tissue Specificity |
Widely expressed in adult (at protein level) and fetal tissues. |
