| Product Name |
Recombinant Human SPEG / APEG-1 Protein |
| Product Overview |
This recombinant human SPEG / APEG-1 protein includes amino acids 1-113aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
Q15772 |
| Recommended Name |
Striated muscle preferentially expressed protein kinase |
| Gene Name |
SPEG |
| Synonyms |
APEG-1;APEG1;BPEG;CNM5;SPEGalpha;SPEGbeta |
| Species |
Human |
| Predicted Molecular Mass |
14 kDa |
| Expression System |
E.coli |
| Expression Range |
1-113aa |
| Tag |
C-His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Developmental Biology |
| Target Function |
Isoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells. |
| Subcellular Location |
[Isoform 3]: Nucleus. |
| Protein Family |
Protein kinase superfamily, CAMK Ser/Thr protein kinase family |
| Associated Diseases |
Myopathy, centronuclear, 5 (CNM5) |
| Tissue Specificity |
Isoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dediffer |
