| Product Name |
Recombinant Human Sodium/Glucose Cotransporter 2 (SGLT2/SLC5A2) Protein |
| Product Overview |
This recombinant human Sodium/Glucose Cotransporter 2 (SGLT2/SLC5A2) protein includes amino acids 548-650aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P31639 |
| Recommended Name |
Sodium/glucose cotransporter 2 |
| Gene Name |
SLC5A2 |
| Synonyms |
SLC5A2; Solute Carrier Family 5 Member 2; Low affinity sodium-glucose cotransporter; Na(+)/glucose c |
| Species |
Human |
| Predicted Molecular Mass |
38 kDa |
| Expression System |
E.coli |
| Expression Range |
548-650aa |
| Tag |
His&TRxA |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction |
| Target Function |
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. |
| Subcellular Location |
Membrane; Multi-pass membrane protein. |
| Protein Family |
Sodium:solute symporter (SSF) (TC 2.A.21) family |
| Associated Diseases |
Renal glucosuria (GLYS) |