| Product Name |
Recombinant Human Solute Carrier Family 30 Member 8 (SLC30A8) Protein |
| Product Overview |
This recombinant human Solute Carrier Family 30 Member 8 (SLC30A8) protein includes amino acids 263-369aa of the target gene is expressed in E.coli.The protein is supplied in liquid or lyophilized powder form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
Q8IWU4 |
| Recommended Name |
Proton-coupled zinc antiporter SLC30A8 |
| Gene Name |
SLC30A8 |
| Synonyms |
ZNT8; Zinc Transporter 8 |
| Species |
Human |
| Predicted Molecular Mass |
16 kDa |
| Expression System |
E.coli |
| Expression Range |
263-369aa |
| Tag |
N-6His |
| Purity |
>95% |
| Formulation |
Liquid or Lyophilized powder |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Others |
| Target Function |
Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle membrane; Multi-pass membrane protein. |
| Protein Family |
Cation diffusion facilitator (CDF) transporter (TC 2.A.4) family, SLC30A subfamily |
| Tissue Specificity |
In the endocrine pancreas, expressed in insulin-producing beta cells. Expressed at relatively high levels in subcutaneous fat tissue from lean persons; much lower levels in visceral fat, whether from lean or obese individuals, and in subcutaneous fat tiss |
