| Product Name |
Recombinant Human Glucose Transporter 1 (GLUT1/SLC2A1) Protein |
| Product Overview |
This recombinant human Glucose Transporter 1 (GLUT1/SLC2A1) protein includes amino acids 251-329aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P11166 |
| Recommended Name |
Solute carrier family 2, facilitated glucose transporter member 1 |
| Gene Name |
SLC2A1 |
| Synonyms |
SLC2A1; SLC2-A1; GLUT; Solute Carrier Family 2 Member 1,Facilitated Glucose Transporter; Glucose tra |
| Species |
Human |
| Predicted Molecular Mass |
13 kDa |
| Expression System |
E.coli |
| Expression Range |
251-329aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Metabolism |
| Target Function |
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Melanosome. Photoreceptor inner segment. |
| Protein Family |
Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily |
| Associated Diseases |
GLUT1 deficiency syndrome 1 (GLUT1DS1); GLUT1 deficiency syndrome 2 (GLUT1DS2); Epilepsy, idiopathic generalized 12 (EIG12); Dystonia 9 (DYT9); Stomatin-deficient cryohydrocytosis with neurologic defects (SDCHCN) |
| Tissue Specificity |
Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues. |
