| Product Name |
Recombinant Human CD27 Binding (CD27BP/SIVA1) Protein |
| Product Overview |
This recombinant human CD27 Binding (CD27BP/SIVA1) protein includes amino acids 1-175aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O15304 |
| Recommended Name |
Apoptosis regulatory protein Siva |
| Gene Name |
SIVA1 |
| Synonyms |
Apoptosis regulatory protein Siva isoform 1, CD27BP, SIVA, Siva-1, Siva-2 |
| Species |
Human |
| Predicted Molecular Mass |
21.1 kDa |
| Expression System |
E.coli |
| Expression Range |
1-175aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cell Biology |
| Target Function |
Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. |
| Subcellular Location |
Cytoplasm. Nucleus. Note=In the nucleus, accumulates in dot-like structures. |
| Tissue Specificity |
Ubiquitous. Mostly expressed in thymus, testis, ovary, prostate, small intestine and spleen and less in colon. |
