| Product Name |
Recombinant Human Signal Regulatory Beta 1 (SIRPb1) Protein |
| Product Overview |
This recombinant human Signal Regulatory Beta 1 (SIRPb1) protein includes amino acids 30-371aa of the target gene is expressed in 293F cell.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
O00241 |
| Recommended Name |
Signal-regulatory protein beta-1 |
| Gene Name |
SIRPB1 |
| Synonyms |
CD172-B; CD172b; SIRP-B1; SIRP-beta-1; CD172 antigen-like family member B |
| Species |
Human |
| Predicted Molecular Mass |
55 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
30-371aa |
| Tag |
C-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Signal Transduction, Others |
| Target Function |
Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK. Triggers activation of myeloid cells when associated with TYROBP. |
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity |
Detected in monocytes and dendritic cells. |
