| Description |
Recombinant Human PRAK Protein is expressed from Baculovirus-Insect Cells with Strep-II tag at the C-terminus.It contains Met1-Gln471. |
| Purity |
> 90% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Accession |
NP_003659.2 |
| Target Symbol |
PRAK |
| Species |
Human |
| Expression System |
Baculovirus-Insect Cells |
| Tag |
C-Strep-II |
| Expression Range |
Met1-Gln471 |
| Mol. Weight |
The protein has a predicted MW of 55.57 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result. |
| Form |
Liquid |
| Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 150mM NaCl, 2mM CaCl2 (pH 8.0). |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping |
Shipped with dry ice. |
| Gene Background |
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway. |
