| Product Name |
Recombinant Human Phosphatase 1, Regulatory Subunit 11 (PPP1R11) Protein |
| Product Overview |
This recombinant human Phosphatase 1, Regulatory Subunit 11 (PPP1R11) protein includes amino acids 10-126aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
O60927 |
| Recommended Name |
E3 ubiquitin-protein ligase PPP1R11 |
| Gene Name |
PPP1R11 |
| Synonyms |
Protein phosphatase 1 regulatory subunit 11, HCG-V, HCGV, IPP3, TCTE5, TCTEX5 |
| Species |
Human |
| Predicted Molecular Mass |
16.3 kDa |
| Expression System |
E.coli |
| Expression Range |
10-126aa |
| Tag |
N-6His |
| Purity |
>95% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Others |
| Target Function |
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2. Inhibitor of protein phosphatase 1. |
| Tissue Specificity |
Widely expressed. |
