| Product Name |
Recombinant Human Cytochrome P450 Reductase (CPR/POR) Protein |
| Product Overview |
This recombinant human Cytochrome P450 Reductase (CPR/POR) protein includes amino acids 77-518aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in PBSprior to lyophilization. |
| Target Uniprot Id |
P16435 |
| Recommended Name |
NADPH--cytochrome P450 reductase |
| Gene Name |
POR |
| Synonyms |
POR; CYPOR; P450R; P450(Cytochrome)Oxidoreductase; NADPH--cytochrome P450 reductase |
| Species |
Human |
| Predicted Molecular Mass |
53 kDa |
| Expression System |
E.coli |
| Expression Range |
77-518aa |
| Tag |
N-6His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
PBS |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Target Function |
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. |
| Subcellular Location |
Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. |
| Protein Family |
NADPH--cytochrome P450 reductase family; Flavodoxin family; Flavoprotein pyridine nucleotide cytochrome reductase family |
| Associated Diseases |
Antley-Bixler syndrome, with genital anomalies and disordered steroidogenesis (ABS1); Disordered steroidogenesis due to cytochrome P450 oxidoreductase deficiency (DISPORD) |
