| Description |
Recombinant Human PODXL2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly33-Thr500. |
| Purity |
> 95% as determined by Tris-Bis PAGE;> 95% as determined by SEC-HPLC |
| Accession |
Q9NZ53 |
| Target Symbol |
PODXL2 |
| Synonyms |
Endoglycan; PODLX2; brain-1; BRN1; EG; oct-8; OTF8; UNQ1861/PRO3742 |
| Species |
Human |
| Expression System |
HEK293 |
| Tag |
C-His |
| Expression Range |
Gly33-Thr500 |
| Mol. Weight |
The protein has a predicted MW of 51.5 kDa. Due to glycosylation, the protein migrates to 85-115 kDa based on Tris-Bis PAGE result. |
| Form |
Lyophilized |
| Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Endotoxin |
Less than 1EU per ug by the LAL method. |
| Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
| Shipping |
Shipped at ambient temperature. |
| Gene Background |
Transmembrane protein endoglycan (PODXL2), which belongs to the CD34-family of highly glycosylated sialomucins. Endoglycan is broadly expressed in the developing mouse brains and is proteolytically shed in vitro in mouse neurons and in vivo in mouse brains. Endoglycan shedding in primary neurons was mediated by the transmembrane protease a disintegrin and metalloprotease 10 (ADAM10), but not by its homolog ADAM17. |
