| Product Name |
Recombinant Human Adenosylmethionine Decarboxylase 1 (AMD1/NPR2) Protein |
| Product Overview |
This recombinant human Adenosylmethionine Decarboxylase 1 (AMD1/NPR2) protein includes amino acids 1-334aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P20594 |
| Recommended Name |
Atrial natriuretic peptide receptor 2 |
| Gene Name |
NPR2 |
| Synonyms |
S-adenosylmethionine decarboxylase proenzyme, ADOMETDC, AMD, DKFZp313L1234, FLJ26964, SAMDC |
| Species |
Human |
| Predicted Molecular Mass |
42 kDa |
| Expression System |
E.coli |
| Expression Range |
1-334aa |
| Tag |
N-6His |
| Purity |
>85% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Cardiovascular, Cancer |
| Target Function |
Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth. |
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. |
| Protein Family |
Adenylyl cyclase class-4/guanylyl cyclase family |
| Associated Diseases |
Acromesomelic dysplasia, Maroteaux type (AMDM); Epiphyseal chondrodysplasia, Miura type (ECDM); Short stature with non-specific skeletal abnormalities (SNSK) |
