Product Name |
Recombinant Human Methionine Sulfoxide Reductase A (MSRA) Protein |
Product Overview |
This recombinant human Methionine Sulfoxide Reductase A (MSRA) protein includes amino acids 27-235aa of the target gene is expressed in E.coli.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
Target Uniprot Id |
Q9UJ68 |
Recommended Name |
Mitochondrial peptide methionine sulfoxide reductase |
Gene Name |
MSRA |
Synonyms |
Methionine sulfoxide reductase A, bA235O14.2, NRK1, RP11-235O14.2. |
Species |
Human |
Predicted Molecular Mass |
27 kDa |
Expression System |
E.coli |
Expression Range |
27-235aa |
Tag |
N-6His |
Purity |
>85% |
Formulation |
Lyophilized |
Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
Research Area |
Metabolism |
Target Function |
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. |
Subcellular Location |
[Isoform 1]: Mitochondrion.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.; [Isoform 5]: Cytoplasm. Membrane; Lipid-anchor. |
Protein Family |
MsrA Met sulfoxide reductase family |
Tissue Specificity |
Ubiquitous. Highest expression in adult kidney and cerebellum, followed by liver, heart ventricles, bone marrow and hippocampus. |