| Product Name |
Recombinant Human Eukaryotic Membrane Spanning 4 Domains Subfamily A, Member 1 (CD20/MS4A1) Protein |
| Product Overview |
This recombinant human Eukaryotic Membrane Spanning 4 Domains Subfamily A, Member 1 (CD20/MS4A1) protein includes amino acids 210-297aa of the target gene is expressed in 293F cell.The protein is supplied in lyophilized form and formulated in phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5% trehaloseprior to lyophilization. |
| Target Uniprot Id |
P11836 |
| Recommended Name |
B-lymphocyte antigen CD20 |
| Gene Name |
MS4A1 |
| Synonyms |
B1;Bp35;CD20;CVID5;LEU-16;MS4A1;MS4A2;S7 |
| Species |
Human |
| Predicted Molecular Mass |
18 kDa |
| Expression System |
Mammalian Cell |
| Expression Range |
210-297aa |
| Tag |
N-His |
| Purity |
>90% |
| Formulation |
Lyophilized |
| Buffer |
Phosphate buffered saline (pH7.4) containing 0.01% sarcosyl, 5%Trehalose |
| Storage Condition |
1. Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. 2. Avoid repeated freeze-thaw cycles. 3. Store working aliquots at 4°C for up to one week. 4. In general, protein in liquid form is stable for up to 6 months at -20°C/-80°C. Protein in lyophilized powder form is stable for up to 12 months at -20°C/-80°C. |
| Reconstitution Instruction |
Briefly centrifuged the vial prior to opening to bring the contents to the bottom. Reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL. It is recommended to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. The default final concentration of glycerol is 50%. |
| Applications |
Positive Control; Immunogen; SDS-PAGE; WB |
| Research Area |
Immunology, Cancer |
| Target Function |
B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. |
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor. |
| Protein Family |
MS4A family |
| Associated Diseases |
Immunodeficiency, common variable, 5 (CVID5) |
| Tissue Specificity |
Expressed on B-cells. |
